When patient concerns centre on skin quality, laxity, early structural change or volume loss, BioFiller protocols offers alternative treatment options beyond traditional volume augmentation strategies with HA filler or synthetic biostimulants.
BioFiller provides a 100% natural, regenerative-focused treatment alternative for appropriately selected patient presentations, that meet clinically-justified indications.
Harness the Regenerative Power of
PLATELET-RICH PLASMA
via BioFiller Australia Technology and Procedure Training
Clinical Protocol FAQ’s
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BioFiller is an autologous (patient’s own biology) volume replacement procedure that combines heat stabilised plasma albumin gel and ‘high-platelet dose’ liquid platelet-rich plasma (PRP) to form the injectable gel. The procedure is performed by an AHPRA-registered, Alocuro-trained healthcare practitioner.
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The heated, volume-stabilised plasma albumin gel provides immediate soft tissue volume restoration and structural support that typically lasts 3–6 months.
While the heating process denatures the plasma protein components, regenerative proteins from the non-heated PRP fraction remain bio-active. So when combined; BioFiller offers both immediate volume replacement and ongoing regenerative benefits through the release of growth factors and proteins from platelets that stimulate collagen production, support overall tissue health which then improves skin quality and appearance.
Patient selection, informed consent, and clinical judgement remain central to treatment planning. Outcomes will vary depending on individual patient factors, treatment technique, and overall clinical approach.
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For clinicians to deliver the best patient benefit, both volume replacement and tissue regeneration is required. Regenerative properties are added to the viscous platelet-poor plasma (PPP) gel by adding a small volume of Alocuro high-platelet dose platelet rich plasma (PRP). This combination injectate is key to delivering volume restoration and skin rejuvenation.
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Biofiller is a non-surgical procedure with a low incidence of complications when performed according to Alocuro and the treating Doctor’s recommended protocols. Common ‘side effects’ may include redness, swelling, and bruising. Because Biofiller is an autologous product (derived from the patient’s own blood), risks associated with other non-surgical procedures - such as allergic reactions, rejection, granuloma formation, or Tyndall effect - are not expected. In the rare event of a vascular occlusion, all practitioners have received training in managing this event within their BioFiller training. All medical procedures carry potential risks, and individual outcomes may vary.
BioFiller Volume Restoration & Tissue Regeneration
Combining Heat-Stabilised Plasma Albumin Gel with High-Concentration PRP
How is Alocuro BioFiller Protocol Unique?
A natural regenerative approach to improve tissue quality and structural support:
Harnesses the patient’s own biological blood components, including high-concentration PRP, for skin rejuvenation and volume restoration.
100% autologous (patient’s own) biomaterial, for promoting regeneration of cells within the microenvironment where it is placed.
Avoids foreign body reaction as it uses solely the patient’s own blood.
Remains moldable during injection and post-procedure.
Capable of stimulating tissue regeneration over extended periods of time.
Due to the platelet-initiated regenerative stimulus to the hypodermis, this tissue health and function improves over time, leading to an improved skin appearance.
A very high platelet-concentration liquid PRP is an essential component to successful BioFiller treatment outcomes. It is only latest technology platelet-concentrating devices, like Alocuro, that can produce the small volume, very high platelet concentration required for this protocol.
Summary of BioFiller Steps:
Consultation: The clinician conducts a thorough medical assessment to determine patient suitability for BioFiller treatment and discusses the injection plan
Blood Collection: 15-30mls of blood is collected to create BioFiller.
Processing: Platelet-rich Plasma The plasma is prepared to provide both volume replacement and regenerative benefits.
Procedure: BioFiller is delivered to areas that require soft tissue support and skin regeneration. Each treatment plan is developed per individual clinical case.
Post Treatment: Mild redness, swelling and/or bruising may occur, and will settle over the following 1-2 weeks.
Outcome: Immediate improvement is visible, with ongoing skin rejuvenation over weeks. Results typically last 3–6 months. *Outcomes vary depending on individual patient factors, treatment technique, and overall clinical approach.
How does Heating & Cooling create Plasma Albumin Gel?
Platelet-poor plasma (PPP) is first ‘activated’ using Alocuro sterile, single-use platelet ‘activator’ device:
The activated PPP is then transferred to the appropriate volume syringes which are sealed with a syringe closure cap, before placing in the BioFiller processor.
The plasma gel is achieved by using the BioFiller processor via:
Precise heating protocol at a stable temperature, followed by
Precise cooling protocol.
Alocuro BioFiller Results
1 x BioFiller treatment by @selfaesthetics.com.au
— Charlotte Wolfenden, Self Aesthetics
Clinical Indication: Facial volume restoration and to improve health and function of the skin via collagen stimulation.