The Patient Journey: What to Expect Before, During, and After Biofiller Treatment
When considering any medical procedure, patients want to know exactly what to expect. This is especially true for treatments in aesthetic and regenerative medicine, where outcomes are influenced by both the science behind the procedure and the patient’s own biology.
Alocuro Biofiller is an autologous injectable treatment that combines plasma gel with concentrated platelets, offering both immediate volume restoration and long-term regenerative benefits. Because it uses the patient’s own blood, it differs from traditional injectates and requires a step-by-step process that patients may not be familiar with.
This article provides a clear overview of the Biofiller treatment journey – from initial consultation to aftercare – so clinicians can set realistic expectations and patients can feel confident and informed.
Stage 1: The Consultation
The consultation is the most important step in ensuring Biofiller is right for the patient. During this session, clinicians will:
Take a medical history: Screening for contraindications such as blood disorders, anticoagulant use, active infection, or uncontrolled systemic disease.
Discuss goals and expectations: Patients may be seeking volume restoration, treatment of hollows, or general skin quality improvements.
Explain treatment options: Comparing Biofiller with traditional alternatives, PRP, or PRF, and advising what’s most appropriate.
Set realistic outcomes: Emphasising that Biofiller provides both immediate and gradual improvements, but results vary depending on age, health, and lifestyle.
Stage 2: Preparing for Treatment
Patients should be given pre-procedure advice to optimise results:
Avoid alcohol, aspirin, and NSAIDs for 48 hours before treatment to reduce bruising risk.
Hydrate well in the days leading up to the procedure, as plasma quality can be influenced by hydration status.
Eat a balanced diet – nutrient-dense foods support healthy platelets.
Refrain from smoking – smoking negatively affects circulation and healing.
Patients should also be advised that they will need a small blood draw (like a standard blood test), so those with a strong aversion to needles should prepare accordingly.
Stage 3: The Procedure – Step by Step
The Biofiller procedure typically takes 45–60 minutes, depending on the treatment areas.
1. Blood Collection
A standard blood draw is performed, usually from the arm.
The volume depends on the treatment plan (commonly 10–20ml).
2. Processing
Blood is placed in the Alocuro PRP system centrifuge, which separates the plasma and platelets from red and white blood cells.
Part of the plasma is heated and cooled to form a gel, creating the volumising component.
This plasma gel is then combined with concentrated platelets to form the Biofiller.
3. Injection
The Biofiller is injected into targeted areas using a cannula.
Common treatment sites may include:
Under-eye hollows
Cheeks
Nasolabial folds
Marionette lines
Preauricular
Back of hands
Clinicians tailor injection technique to balance immediate soft tissue volumisation with regenerative distribution.
Patients may feel mild pressure during injections, but topical anaesthetic or local numbing techniques may be offered for comfort.
Stage 4: Immediately After Treatment
Patients typically notice immediate improvement due to the plasma gel. Unlike HA fillers, the volume is softer and more subtle.
Normal post-procedure experiences include:
Mild redness or swelling at injection sites
Bruising (varies depending on area and individual)
Temporary tenderness
Patients are usually able to return to daily activities the same day, though strenuous exercise and alcohol should be avoided for 24–48 hours.
Stage 5: Short-Term Recovery (First 2 Weeks)
During the first two weeks:
Any swelling or bruising will settle.
Plasma gel integrates into tissue, providing natural-looking support.
Platelets release growth factors, starting the regenerative process.
Patients should be advised to avoid massaging the treated area unless directed, as this could affect product placement.
Stage 6: Long-Term Results (2–6 Months)
The most significant difference between Biofiller and traditional synthetic products is the ongoing improvement over time.
2–4 weeks: Fibroblasts are activated, beginning collagen and elastin production.
1–3 months: Skin quality improves, with increased elasticity and better texture.
3–6 months: Angiogenesis (new blood vessel formation) supports healthier tissue, enhancing tone and resilience.
Results can last 6–12 months or more, with the regenerative benefits sometimes extending beyond the volumising effect.
Maintenance and Repeat Treatments
Patients may benefit from a series of treatments depending on their goals:
Mild changes/early aging: One session may be sufficient.
Moderate volume loss or skin laxity: Two to three sessions, spaced 4–6 months apart, may provide optimal results.
Ongoing maintenance: Annual touch-ups are often recommended.
Risks and Considerations
Although Biofiller is autologous and generally well tolerated, clinicians should always discuss potential risks:
Bruising, swelling, or discomfort at injection sites
Infection (rare, but possible if aseptic technique is not followed)
Temporary unevenness (usually resolves as tissue integrates)
Vascular Occlusion (there have been no reported cases, however the risk is still a possibility)
Who Is (and Isn’t) a Candidate?
Ideal candidates:
Patients seeking natural, gradual improvements
Those with early-to-moderate signs of aging
Patients hesitant about synthetic fillers
Not suitable for patients with:
Blood clotting disorders
Active infections at the treatment site
Severe systemic illness
Very advanced aging requiring surgical intervention
The Role of the Clinician
One of the greatest strengths of Biofiller is its ability to be tailored. Successful outcomes depend heavily on:
Accurate patient assessment – understanding anatomy, goals, and limitations.
Injection technique – using the right depth and placement for both volumising and regenerative effects.
Education – ensuring patients understand both the immediate and long-term nature of results.
Frequently Asked Questions
1. How soon will I see results?
Immediately after treatment, with improvements continuing over 2–6 months.
2. How long does Biofiller last?
Typically 6–12 months, but regenerative effects may extend beyond this timeframe.
3. Can it be combined with other treatments?
Yes. Biofiller can complement microneedling, PRP, or laser treatments for enhanced results.
4. Is it reversible like HA fillers?
No – Biofiller is naturally absorbed over time.
5. Is it safe?
Because it’s made from your own blood, risks of allergy or foreign-body reaction are very low.
Conclusion
The patient journey with Alocuro Biofiller is a balance of immediate volume restoration and gradual regenerative enhancement. From consultation through aftercare, success lies in aligning patient expectations with the biological mechanisms at work.
For patients, this means a natural, progressive improvement in volume, skin quality, and tissue health. For clinicians, Biofiller represents a treatment philosophy that goes beyond surface-level correction, supporting long-term regenerative outcomes.
